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In these studies, people took Vyvanse or a placebo (a treatment containing no active drug) for 12 weeks
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Brain-derived GLP-1 is synthesized in a subset of neurons in the NTS that project to GLP-1R–expressing regions in the hindbrain and hypothalamus, including the paraventricular nucleus (PVN), dorsal medial nucleus of the hypothalamus, and arcuate nucleus (ARC), as well as the NTS itself
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