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In this regard, the activation of areas outside the blood-brain barrier (BBB) could have relevant effects on eating, since peripherally injected 125 I-labeled GLP-1 binds to the subfornical organ and the AP, which both have close neuroanatomical connections with hypothalamic areas involved in water and appetite homeostasis [196]
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Effects of Dietary Composition on Energy Expenditure During Weight-Loss Maintenance
