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Several clinical trials have demonstrated that most of GLP-1RAs improve these parameters and thus attenuate the development and progression of atherosclerosis, especially concerning low-density lipoprotein cholesterol (LDL-C) levels [33]
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Glimepiride in Type 2 Diabetes) with linagliptin comparing linagliptin treatment as add on to metformin directly with a therapy with the sulfonylurea glimepiride will bring results later in 2019 and may give additional insights into the association and mechanisms linking hypoglycaemic- with cardiovascular events (69)
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