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Frontiers | DPP-4 Inhibitors as Potential Candidates for Antihypertensive Therapy: Improving Vascular Inflammation and Assisting the Action of Traditional Antihypertensive Drugs

Thus, metformin inhibits mitochondrial respiratory chain complex IV, indirectly inhibiting mGPDH activity [26]

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Regarding specific adverse reactions, the most reported were gastrointestinal events