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“This dual mechanism may explain the absence of early-worsening effects and the apparent protective association observed in our real-world cohort.” They concluded that prospective studies that incorporate standardized retinal imaging and extend follow-up are needed to confirm the durability of this benefit and to refine recommendations for patients considering weight loss medications who are at risk for DR
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Significant reductions in body weight and HbA1c levels were observed across all three tirzepatide dosage groups
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