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Currently, Semaglutide is only FDA-approved for obesity and to help with blood sugar control in type-2 diabetes and to lower the risk of major cardiovascular events (like heart attack and stroke) in people with both type-2 diabetes and heart disease
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Because these receptors participate in interconnected metabolic pathways, dual receptor agonists such as tirzepatide allow researchers to investigate receptor cross-talk, signaling bias, and multi-pathway modulation in controlled experimental environments [2]
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