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In tirzepatide, dual agonism of GIP and GLP-1 receptors may amplify these effects via: Enhanced insulinotropic action Greater suppression of appetite Synergistic modulation of fat metabolism This is an area of active research — and an example of rational drug design rooted in receptor biology

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Silva specializes in evidence-based weight management, including the expert management of diarrhea and other GI side effects common with GLP-1 and GIP therapies such as semaglutide and tirzepatide