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Unlike FDA-approved drugs, compounded versions have not been proven to be safe, effective or consistently manufactured. https://www.kxan.com/news/ compounded-glp-1 -drugs-creating-concern-among-doctors-and-fda/?utm_medium=social&utm_source=facebook_KXAN_News
Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: A systematic review and meta-analysis of randomised controlled trials
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In Roux-en-Y gastric bypass (RYGB) surgery patients, octreotide (a somatostatin analog) suppressed post-prandial plasma GLP-1 levels, which correlated with palatable food reward in a progressive ratio task, food appeal scores, and increased activation of important reward system areas such as NAc, caudate, anterior insula, and amygdala
