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7.3 From PCOS to “endotypes”: the role of ML in stratification over promises The diagnostic label of PCOS encompasses a highly heterogeneous pathophysiological spectrum

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Cash Pay Options Manufacturer Direct Programs: Novo Nordisk: $199/month for first two doses, then $349/month Eli Lilly LillyDirect: $299-$499/month depending on dose TrumpRx Platform (Launching Early 2026): Injectable GLP-1s: $350/month initially, dropping to $250 within 2 years Oral GLP-1s (pending FDA approval): $149/month for starting doses GoodRx/Discount Cards: Prices vary by pharmacy and location Typically $900-$1,200/month without manufacturer programs Check current prices at your local Hinsdale pharmacies Cost Comparison: What You'll Actually Pay Ozempic (semaglutide for diabetes): Insurance copay: $25-$100/month Medicare (2026): $50/month Cash (manufacturer direct): $199-$349/month List price: $969/month Wegovy (semaglutide for obesity): Insurance copay: Often not covered Medicare (2026): $50/month Cash (manufacturer direct): $199-$349/month List price: $1,349/month Mounjaro (tirzepatide for diabetes): Insurance copay: $25-$100/month Medicare (2026): $50/month List price: $1,069/month Zepbound (tirzepatide for obesity): Insurance copay: Often not covered Medicare (2026): $50/month Cash (manufacturer direct): $299-$499/month List price: $1,059/month At Well Endocrinology, we help patients navigate insurance coverage, prior authorizations, and manufacturer savings programs to minimize out-of-pocket costs