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The choice of procedure is made collaboratively between the patient and the MDT, taking into account individual clinical factors, patient preference, and the presence of conditions such as gastro-oesophageal reflux disease (GORD) — which may favour bypass over sleeve in some cases
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Side Effect Profile Both medications share similar side effects, primarily because of the overlapping GLP-1 mechanism: Nausea — most common, especially when starting or increasing dose Vomiting — typically mild and improves over time Diarrhea or constipation — varies by patient Fatigue — common in the first weeks Reduced appetite — the desired effect, but can lead to insufficient nutrition if not managed Does tirzepatide cause more side effects
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