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Most first-line antihypertensive drug classes such as ACE inhibitors, angiotensin receptor blockers, thiazide diuretics, and calcium channel blockers lower systolic BP by roughly 5–15 mmHg on average in hypertensive patients, depending on baseline BP and dose [32, 33, 34, 35]
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![PDF] Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide](https://figures.semanticscholar.org/594349790d0e9a09f8b5843f2782af9cfaaa7bf4/37-Figure3-1.png)
