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However, lixisenatide inhibited the Aβ-induced activation of GSK-3β, with a significant increase in the phosphorylation of ser9 and a significant decrease in the phosphorylation of Y216, suggesting that lixisenatide can prevent Aβ-related impairments by affecting the PI3K-Akt-GSK3β pathway (179)

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The Dopamine Connection GLP‑1 receptors are involved in brain pathways connected to reward, appetite, motivation, and impulse regulation