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[DOI] [PubMed] [Google Scholar] 26.Holman RR, Bethel MA, Mentz RJ, Thompson VP, Lokhnygina Y, Buse JB, Chan JC, Choi J, Gustavson SM, Iqbal N
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Semaglutide activates GLP-1 receptors, while tirzepatide is a dual-action medication that activates both GLP-1 and GIP receptors — and in clinical research it has produced greater average weight loss