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They have been optimized by millions of years of evolution to disrupt specific physiological processes—precisely the characteristics sought in drug development
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[DOI] [PubMed] [Google Scholar] Davis JF, Schurdak JD, Magrisso IJ, Mul JD, Grayson BE, Pfluger PT, Tschöp MH, Seeley RJ, Benoit SC, 2012