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Appendix Abbreviations ACTH adrenocorticotropic hormone AMH anti-Müllerian hormone BMI body mass index BP blood pressure COCPs combined oral contraception pills CPA cyproterone acetate DHEA dehydroepiandrosterone DHEA-S dehydroepiandrosterone sulfate DHT dihydrotestosterone EE ethinylestradiol FAI free androgen index FBG fasting blood glucose FDA Food and Drug Administration FN1 fibronectin 1 FSH follicular stimulating hormone FT free testosterone GIP glucose-dependent insulinotropic polypeptide GLP-1 glucagon-like peptide-1 GLP-1RA glucagon-like peptide-1 receptor agonist GLP-1RAs glucagon-like peptide-1 receptor agonists GnRH gonadotropin-releasing hormone HbA1c hemoglobin A1c HDL high-density lipoprotein HOMA-IR homeostatic model assessment of insulin resistance HPA hypothalamic-pituitary-adrenal HPG hypothalamic-pituitary-gonadal IL interleukin IR insulin resistance IVF in vitro fertilization LH luteinizing hormone MetS metabolic syndrome MR-proADM mid-regional pro-adrenomedullin MR-proANP mid-regional pro-atrial natriuretic peptide NAFLD nonalcoholic fatty liver disease OCPs oral contraception pills OGTT oral glucose tolerance test PCOS polycystic ovarian syndrome PIIINP procollagen type 3 amino-terminal peptide PRDX6 peroxiredoxin 6 RAAS renin-angiotensin-aldosterone system RCT randomized control trial ROS reactive oxygen species SHBG sex hormone-binding globulin T2DM type 2 diabetes mellitus TC total cholesterol TG triglycerides TNF-α tumor necrosis factor-alpha TZDs thiazolidinediones WC waist circumference WHR waist-to-hip ratio Footnotes ORCID iDs: Bassel H